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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: DNA Repair (Amst). 2015 Jan 6;0:9–18. doi: 10.1016/j.dnarep.2014.12.006

Figure 1.

Figure 1

Figure 1

Labeling AP sites with alkoxyamines. (A) The open-chain aldehyde of an AP site in DNA reacts with alkoxyamines (Methoxyamine, AA3 or ARP). (B) Use of click chemistry to label AA3 adducted DNA (★ can be biotin, a fluorophore or any other molecule).