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. Author manuscript; available in PMC: 2015 Feb 25.
Published in final edited form as: Adv Healthc Mater. 2014 Aug 22;4(3):367–376. doi: 10.1002/adhm.201400336

Figure 4.

Figure 4

Clearance and biodistribution of PAMs. Representative, whole body, in vivo optical images of ApoE knock-out mice treated with A) MCP-1 PAMs or scrambled PAMs. Arrows point to the liver and the bladder. B) Quantification of the Cy7 fluorescence signal in urine. Data points are mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001, ***P < 0.0001 compared to the PBS-treated group. C) Ex vivo imaging of the heart, lung, liver, spleen, large intestines, kidney, and bladder treated with MCP-1 PAM, scrambled PAM, or PBS.