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Anticancer activity (72 h) and EGFR inhibitory potential.
| Inhibition of cell growth [IC50 μm] | EGFR inhibition [IC50, nm] | |||
|---|---|---|---|---|
| Compound | A431 | Calu3 | H1975 | |
| erlotinib | 2.6±0.8 | 0.74±0.02 | >25 | 2[17] |
| L1 | >25 | 3.5±0.1 | 20±4 | 1.34 |
| L2 | 9.2±0.5 | 2.0±0.5 | 15±2 | 0.95 |
| L3 | >25 | >25 | >25 | 4.59 |
