Table I. White matter regions of fractional anisotropy reduction between nonresponders and responders at baseline. JHU, Johns Hopkins University; MNI, Montreal Neurological Institute. a Obtained by dividing the number of significant voxels within each regional mask by the total number of voxels in that mask. From reference 33: Reis Marques TR, Taylor H, Chaddock CA, et al White matter integrity as predictor of response to treatment in first episode psychosis. Brain. 2014;137:172-182. © 2013, Oxford University Press.
| JHU white matter atlas region | Significant cluster size (n° voxels) | Region significant (%)a | t-statistic | MNI coordinates of peak voxel (mm) | ||
| X | Y | Z | ||||
| Uncinate | ||||||
| Left | 70 | 91% | 3.38 | -33 | -6 | -14 |
| Right | 59 | 86% | 2.24 | 35 | -4 | -14 |
| Fornix | ||||||
| Left stria terminalis | 270 | 76% | 2.98 | -34 | -11 | -15 |
| Right stria terminalis | 11 | 4% | 2.64 | 34 | -11 | -15 |
| Corticospinal | ||||||
| Left | 203 | 75% | 1.92 | 9 | -29 | -23 |
| Right | 135 | 51% | 3.02 | 10 | -27 | -27 |
| Cerebral peduncle | ||||||
| Left | 436 | 72% | 2.35 | -9 | -29 | -20 |
| Right | 360 | 59% | 3.40 | 10 | -28 | -19 |
| External capsule | ||||||
| Right | 781 | 67% | 2.48 | 36 | -7 | -13 |
| Left | 790 | 61% | 4.36 | -35 | -8 | -13 |
| Internal capsule | ||||||
| Left posterior limb | 575 | 66% | 2.64 | -20 | -14 | 0 |
| Right anterior limb | 480 | 58% | 3.24 | 10 | 1 | 1 |
| Left retrolenticular limb | 372 | 47% | 2.44 | -24 | -19 | 0 |
| Left anterior limb | 361 | 43% | 3.00 | -13 | -1 | 4 |
| Corpus callosum | ||||||
| Body | 1985 | 63% | 2.70 | -13 | 17 | 24 |
| Genu | 1039 | 60% | 3.55 | -15 | 32 | 14 |
| Splenium | 1145 | 46% | 2.13 | 1 | -31 | 21 |
| Corona radiata | ||||||
| Right anterior | 1005 | 63% | 3.26 | 27 | 28 | 10 |
| Left anterior | 942 | 56% | 3.75 | -15 | 33 | 15 |
| Left posterior | 364 | 48% | 1.27 | -21 | -44 | 35 |
| Left superior | 578 | 42% | 2.36 | -22 | -25 | 36 |
| Right superior | 591 | 42% | 3.21 | 21 | -16 | 36 |
| Right posterior | 153 | 20% | 2.67 | 30 | -60 | 19 |
| Cerebellar peduncle | ||||||
| Left superior | 99 | 48% | 2.16 | -5 | -30 | -21 |
| Right superior | 90 | 36% | 2.46 | 7 | -31 | -16 |
| Left inferior | 66 | 33% | 1.97 | -13 | -45 | -32 |
| Middle | 753 | 33% | 3.19 | -23 | -46 | -36 |
| Pontine cross tract | 98 | 25% | 2.35 | -2 | -30 | -30 |
| Medial lemniscus | ||||||
| Left | 61 | 24% | 2.13 | -4 | -38 | -37 |
| Right | 30 | 12% | 2.10 | 6 | -34 | -25 |
| Superior frontal occipital | ||||||
| Right | 18 | 23% | 1.52 | 23 | 2 | 19 |
| Left | 9 | 10% | 1.45 | -21 | 5 | 19 |