Table II. White matter regions of fractional anisotropy reduction between nonresponders and responders at 12-weeks follow-up. JHU, Johns Hopkins University; MNI, Montreal Neurological Institute. -'Obtained by dividing the number of significant voxels within each regional mask by the total number of voxels in that mask. From reference 33: Reis Marques TR, Taylor H, Chaddock CA, et al White matter integrity as predictor of response to treatment in first episode psychosis. Brain. 2014;137:172-182. © 2013, Oxford University Press.

JHU white matter atlas region	Significant cluster size (n° voxels)	Region significant (%)a	t-statistic	MNI coordinates of peak voxel (mm)
				X	Y	Z
Uncinate
Left	58	81%	2.48	-34	-6	-14
Right	65	96%	1.88	36	-3	-16
External capsule
Left	831	64%	4.61	-33	-6	-13
Right	341	29%	2.55	36	-7	-13
Corona radiata
Left anterior	1014	59%	2.70	-15	36	-1
Right anterior	978	59%	3.49	23	19	18
Left superior	760	54%	3.56	-22	-25	35
Right superior	292	21%	3.47	23	-19	38
Left posterior	406	53%	2.19	-26	-30	27
Right posterior	21	3%	1.76	19	-26	35
Fornix
Left stria terminalis	202	58%	2.55	-28	-26	-8
Right stria terminalis	10	3%	2.63	34	-11	-15
Internal capsule
Left anterior limb	446	53%	2.51	-17	6	9
Right anterior limb	327	39%	3.13	21	4	15
Left retrolenticular limb	286	36%	2.01	-26	-24	8
Left posterior limb	160	18%	1.42	-22	-9	11
Right posterior limb	88	10%	2.25	20	-4	10
Corpus callosum
Genu	806	46%	2.91	-13	33	-3
Body	725	23%	3.01	15	17	25
Splenium	377	15%	2.10	-23	-54	17
Superior frontal occipital
Left	34	35%	2.25	-21	14	19
Right	26	32%	1.27	23	2	19
Superior longitudinal fasciculus
Left	331	24%	2.36	-35	-25	35
Right	367	24%	1.89	38	-39	28
Thalamic radiation
Left posterior	207	19%	1.73	-28	-53	18
Inferior longitudinal fasciculus
Left sagittal stratum	38	8%	2.54	-35	-11	-14
Right sagittal stratum	7	1%	2.19	36	-11	-14
Cingulum
Right	25	7%	2.30	10	17	26