. Author manuscript; available in PMC: 2015 Sep 1.

Published in final edited form as: Curr Opin Pulm Med. 2014 Sep;20(5):429–435. doi: 10.1097/MCP.0000000000000074

Table 1. Summary of studies supporting association of rs35705950 minor allele with IPF.

This table summarizes the published literature confirming the association between the rs35705950 minor allele and IPF that was originally described in 2011 by Seibold and colleagues [16].

Location	IPF (% SNP)	Controls (% SNP)	Odds Ratio (GT vs GG)	Odds Ratio (TT vs GG)	p-value	Reference
USA	367 (60.8%)	802 (20.7%)	5.7 (4.3-7.5)	9.6 (4.7-19.4)	8.9×10^-41	Zhang et al. NEJM 2011 [26]
UK	110 (67.0%)	416 (19.6%)	6.6 (4.1-10.7)	11.8 (4.3-33.7)	2.0×10^-17	Stock et al. Thorax 2013 [27*]
France	142 (65.5%)	1383 (20.2%)	6.4 (4.5-9.0)	19.1 (9.0-36.1)	9.0×10^-29	Borie et al. PLoS One 2013 [28*]
USA	2492 (63.1%)	1890 (19.6%)	4.5 (3.9-5.2) - overall		7.2×10^-95	Fingerlin et al. Nat Genetics 2013 [17**]
USA	324 (57.2%)	702 (21.3%)	2.4 (2.1-2.8) - overall		2.4×10^-50	Noth et al. Lancet Resp 2013 [18*]