Skip to main content
. 2014 Nov 25;34(2):184–199. doi: 10.15252/embj.201489527

Figure 4. Inverse correlation between acetyl- and SUMO2-FXR levels during the development of diet-induced obesity.

Figure 4

  • A Experimental outline.
  • B–D Effects of feeding a HFD as a function of time on mRNA levels of the indicated genes (B), levels of SUMO2-modified FXR (C), and levels of acetylated and SUMO2-modified proteins (D) in mouse liver (pooled from 3 mice). Values in (B) are presented as mean ± SEM; two-tailed Student's t-test, *P < 0.05, **P < 0.005, n = 3.