Table 1.
Baseline characteristics of the LTBI screening candidates
| Demographics | Number (n = 48) |
|---|---|
| Age; median [range] | 38 [22–67] |
| Gender | |
| Female | 15 (31%) |
| Male | 33 (69%) |
| Ethnic origin | |
| Sub Saharan | 22 (46%) |
| Caucasian | 18 (38%) |
| North African | 3 (6%) |
| Asian | 3 (6%) |
| South American | 2 (4%) |
| Mtb exposure risk factors | |
| Presence of at least one major Mtb exposure risk factor | 23 (48%) |
| Born in high incidence countrya | 22 (46%) |
| Arrival in low incidence country ≤ 2 years | 4 (8%)b |
| Self-reported close contact with a case of TB | 1 |
| Close contact with a case of sputum positive TB | 1 |
| Otherc | 5 (10%) |
| Visitors of endemic countriesd | 14 (29%) |
| LTBI reactivation risk factors | |
| Presence of ≥ 1 reactivation risk factor other than HIV | 5 (10%) |
| Diabetes | 2 (4%) |
| Body mass index < 18,5 | 2 (4%) |
| Renal insufficiency +/− dialysis | 1 |
| Solid tumor | 1 |
| Alcoholism | 1 |
| Self-reported BCG vaccination status | |
| Vaccinated | 16 (33%) |
| Not vaccinated | 17 (35%) |
| Unknown | 15 (31%) |
| HIV infection parameters | |
| HIV-1 | 47 (98%) |
| HIV-2 | 1 |
| Seroconversion ≤ 2 years | 9 (19%)e |
| CD4+ T-cell count; median [range] | 517 [1–1065] |
| Viral load; median [range] | 23242 [<40-1.107]f |
Units: Age (years); CD4+ T-cell count (cells/mm3); viral load (copies/ml).
a>100 cases of TB/ 100000 inhabitants.
bRepresents 17% of those born in a high incidence country.
cProfessional risk, previous incarceration, asylum seeker, homeless.
dConcerns the patients born in low incidence country.
eDate of HIV seroconversion unknown for 40% of the enrolled subject.s
fThe patient with an undetectable viral load is an elite controller (HIV-2 infected).