Table 3.
Effect of HIV on PPD and HBHA induced IFN-γ levels
| IFN-γ conc. in response to PPD-stimulation | IFN-γ conc. in response to HBHA-stimulation | |||||
|---|---|---|---|---|---|---|
| n | p | r | n | p | r | |
| CD4+ T-cell count | 43 | 0.1499 | 0.2261 | 42 | 0.9029 | −0.0192 |
| CD4+ % | 42 | 0.0034 | 0.4473 | 41 | 0.5827 | 0.0873 |
| CD4+/CD8+ ratio | 43 | <0.0001 | 0.8586 | 42 | 0.4265 | 0.1245 |
| Viral load | 41 | 0.5777 | −0.0896 | 41 | 0.4643 | −0.1175 |
Pearson correlation was used to measure the association between PPD- or HBHA-induced IFN-γ responses and four different predictor variables associated with HIV-infection severity: absolute CD4+ T-cell counts, CD4+ percentages (%), CD4+/CD8+ ratios and viral loads. Significant p values are in bold type (p < 0.05). conc = concentration; n = number of tests; r = pearson's product moment coefficient.