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Box and whisker plots of the estimation errors for ddQTc in different Tmax scenarios of both TQT and phase 1 studies. Linear mixed effect model 2 was selected as the best model and difference between true ddQTc (true concentration × true slope) and model-predicted ddQTc (observed concentration x slope estimates) were calculated in ms. Boxes denote the 25th and 75th percentiles and closed circle inside the box denotes the median. Whiskers represent the 5th and 95th percentiles.
