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. 2015 Feb 8;2015:146389. doi: 10.1155/2015/146389

Table 3.

Comparison between MDK at cutoff value 0.387 ng/mL and AFP at cutoff values 88.5, 20, and 200 ng/mL regarding sensitivity and specificity in diagnosis of HCC.

Cutoff Sensitivity Specificity
% P % P
Midkine versus  
AFP
0.387  
88.5
92.5  
40
0.001*
HS
83.3  
96.7
0.195**
NS

Midkine versus  
AFP
0.387  
20
92.5  
62.5
0.001*
HS
83.3  
53.3%
0.012*
S

Midkine versus  
AFP
0.387  
200
92.5  
25.0%
0.001*
HS
83.3  
100
0.052**
NS

MDK: midkine; AFP: alpha-fetoprotein.

*Chi-square test.

**Fisher's exact test.