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. 2015 Jan 24;3(Spec Iss 3):S0044. doi: 10.5702/massspectrometry.S0044

Table 2. Potential candidate RCC biomarker peptides down-regulated following surgery.

Peptide No. Intensity ratios of reporter ions of TMT Charge m/z 6 plex-TMT1) No. reactive site Molecular weight2) Gene name Amino acid sequence
127/126 129/128 131/130 Average
a1 0.76 0.58 0.62 0.65 2 449.6940 1 668.2105 Not identified
a2 0.41 0.63 0.40 0.48 2 492.7200 1 754.2626 Not identified
a3 0.70 0.63 0.59 0.64 2 501.7249 1 772.2723 Not identified
a4 0.61 0.66 0.60 0.62 2 522.7354 1 814.2932 Not identified
a5 0.70 0.43 0.26 0.46 3 516.5599 2 1088.3321 Not identified
a6 0.63 0.50 0.46 0.53 4 545.0582 3 1488.7150 Not identified
a7 0.72 0.66 0.43 0.60 5 528.5377 5 1491.8373 Not identified
a8 0.74 0.55 0.59 0.63 5 482.7059 4 1491.8413 Not identified
a9 0.61 0.56 0.55 0.57 2 985.0003 1 1738.8231 Not identified
a10 0.68 0.76 0.74 0.73 3 746.1359 2 1777.0601 Not identified
a11 0.43 0.45 0.78 0.55 3 835.7786 2 2045.9880 Not identified
a12 0.75 0.70 0.60 0.68 4 815.4955 4 2341.3011 Not identified
a13 0.30 0.40 0.58 0.43 5 672.1757 2 2897.5161 Not identified

1) The observed m/z of precursor ion of each potential candidate peptide labeled with 6 plex-TMT. 2) Molecular weight was calculated from observed m/z of 6 plex-TMT.