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. Author manuscript; available in PMC: 2015 Feb 23.
Published in final edited form as: Auton Neurosci. 2012 Dec 11;175(0):9–16. doi: 10.1016/j.autneu.2012.11.008

Fig. 5.

Fig. 5

Baroreflex sensitivity was significantly (p < 0.0001) reduced after bilateral injection of SP-SAP into the NTS. The baroreflex was tested in 8 rats anesthetized with chloralose. Reflex bradycardia in response to pressor effects of varying doses of phenylephrine and tachycardia in response to depressor effects of nitroprusside were assessed and analyzed by regression analysis. Because there was no significant difference in baroreflex responses at 1 week (n=5) and 2 weeks (n=3) after administering SP-SAP, data were combined in this analysis. Baroreflex sensitivity was also decreased in animals treated with anti-DBH-SAP (not shown here) whether measured by assessing changes in HR following pressor or depressor responses to phenylephrine or nitroprusside respectively or by sequence analysis (Talman et al., 2012). From Riley et al as permitted (Riley et al., 2002)