a. Increasing NIH Funded Research in Neuroepigenetics. Figure 1a shows the cumulative number of funded R01 epigenetic/epigenomic grants from 2005–2013 from three neuroscience-focused NIH institutes: National Institute on Drug Abuse (NIDA), National Institute on Mental Health (NIMH), and National Institute of Neurological Disorders and Stroke (NINDS). These data were obtained by searching NIH Reporter (http://projectreporter.nih.gov/reporter.cfm) in June 2014 for funded grants that used the terms epigenetic or epigenomic in their abstract or specific aims.
b. Increasing Numbers of Non-review Publications in Neuroepigenetics. Figure 1b shows the increasing number of non-review publications over time in the area of epigenetics or epigenomics in the nervous system. PubMed (http://www.ncbi.nlm.nih.gov/pubmed) was searched in June 2014 for titles or abstracts that mention epigen (to capture epigenetics or epigenomics) and a nervous system term (nervous system, or neuro or brain). The search was performed to capture only non-review publications.