FIG. 2.
Weight, grip strength, and histological analyses of Cre-mediated recombination in Cre-ER™-VCPR155H/+ mice. (a) Weight analysis and (b) grip strength measurements of WT and Cre-ER™-VCPR155H/+ tamoxifen-treated animals at 3, 9, 15, and 18 months of age, respectively. Histological analyses by H&E in (c) corn oil control or tamoxifen-treated WT and Cre-ER™-VCPR155H/+ mice. Black arrow indicates centralized nuclei and degenerating fibers (blue arrow). Scale bar represents 100 μm. Statistical significance is denoted by *p<0.05. The number of animals used was n=8–10/group. Color images available online at www.liebertpub.com/hgtb