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(a and b) MicroCT analyses of hind limb bones in WT and Cre-ER™-VCPR155H/+ mice. (c and d) Gross microCT images of hind limb bones in WT and Cre-ER™-VCPR155H/+ mice. The number of animals used was n=8–10/group. (d) Paget-like lytic lesion in VCPR155H/+ control mouse is shown by an arrow in the left panel, whereas the tamoxifen-treated VCPR155H/+ mouse depicted no lesions in the right panel. MicroCT, micro-computed tomography. Color images available online at www.liebertpub.com/hgtb
