TABLE 5.
Pairwise comparisons of Coronaviridae-wide conserved domains in replicase polyprotein 1ab between ChRCoV HKU24 and other lineage A betacoronaviruses
| Replicase polyprotein domain | Pairwise amino acid sequence identity with the ChRCoV HKU24 sequence (%) |
|||
|---|---|---|---|---|
| Betacoronavirus 1 | RbCoV HKU14 | Murine coronavirus | HCoV HKU1 | |
| nsp3 (ADRP) | 74.8–81.7 | 74.8 | 69.5–70.2 | 71 |
| nsp5 (3CLpro) | 85.8–86.8 | 86.8 | 82.5–82.8 | 82.2 |
| nsp12 (RdRp) | 91.8–92.6 | 92.5 | 90.3 | 88.1 |
| nsp13 (Hel) | 93.4–94.8 | 94.7–94.8 | 90.5–90.7 | 88.9–89.1 |
| nsp14 (ExoN) | 86.4–88.7 | 88.7 | 83.9–84.1 | 80.2 |
| nsp15 (NendoU) | 77.6–79.2 | 79.5 | 72.0–73.6 | 70.1 |
| nsp16 (O-MT) | 88.7–89.7 | 89.1 | 83.8–85.1 | 84.1 |