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. 2014 Dec 31;89(6):3163–3175. doi: 10.1128/JVI.03353-14

FIG 1.

FIG 1

Comparative strand transfer activities of purified HIV-1 WT integrase and variant integrase proteins of CRF02_AG, subtype C, and subtype B origins. (A) Target DNA saturation (0 to 128 nM) plots showing the activity of CRF02_AG (AG) proteins in the presence of fixed protein and LTR concentrations (300 nM and 160 nM, respectively). (B) Target DNA saturation plots showing the activity of subtype C proteins in the presence of fixed protein and LTR concentrations (300 nM and 160 nM, respectively). (C) Comparison of strand transfer reaction efficiencies for CRF02_AG, subtype B, and subtype C integrase proteins. All data presented reflect at least three independent experiments, each performed in duplicate or triplicate.