FIG 5 .

Coccidian-specific protein families implicated in virulence and host range determination. (A) Maximum-likelihood-based phylogenetic tree of the ROPK family. Values indicate the bootstrap support (of 1,000 replicates). S. neurona members are red. T. gondii members are dark blue. N. caninum members are cyan. T. gondii and N. caninum clades are blue. E. tenella members and clades are yellow. (B) Summary of the 23 SRS family members identified in the S. neurona genome. Relative expression in the S. neurona merozoite stage are provided as FPKM values, and domain architectures are indicated. #ESTs, number of expressed sequence tags. (C) The expression of the SnSRS-encoding genes was assessed by TaqMan qPCR. Genes were sorted in descending order by their expression levels.