Table 3.
Allele frequencies and carriage rates of MEFV variants in patients with adult-onset Still's disease (AOSD)
| AOSD patients (n = 49) | Healthy subjects (n = 105) | P-value | ||
|---|---|---|---|---|
| Allele frequencies (%) | ||||
| Exon 10 | M694I | 2 (2·0) | 0 | 0·101 |
| G632S | 1 (1·0) | 0 | 0·318 | |
| Exon 3 | P369S | 6 (6·1) | 13 (6·2) | 0·982 |
| R408Q | 5 (5·1) | 12 (5·7) | 0·827 | |
| Exon 2 | L110P | 8 (8·2) | 15 (7·1) | 0·751 |
| E148Q | 29 (29·6) | 52 (24·8) | 0·370 | |
| R202Q | 4 (4·1) | 6 (2·9) | 0·399 | |
| G304R | 0 | 6 (2·9) | 0·098 | |
| Exon 1 | E84K | 2 (2·0) | 2 (1·0) | 0·380 |
| Carriage rate (%) | ||||
| Total exon 10 variants | 3 (6·1) | 0 | 0·031 | |
| Total exon 1,2,3 variants | 28 (57·1) | 61 (58·1) | 0·911 | |
| Total MEFV variants | 31 (63·3) | 61 (58·1) | 0·542 |