Table 2.
Mean value of cytokine concentration ± standard error of the mean in children with chronic hepatitis B (CHB) and healthy controls
CHB patients (n = 18) | Healthy controls (n = 16) | P-value | |
---|---|---|---|
IFN-γ | 162 ± 87 | 170 ± 103 | 0·98 |
IFN-α | 86 ± 42 | 57 ± 30 | 0·56 |
TNF-α | 315 ± 312 | 1003 ± 685 | 0·83 |
TNF-β | 1424 ± 574 | 1391 ± 873 | 0·75 |
IL-10 | 13 ± 5 | 6 ± 3 | 0·56 |
IL-12 | 195 ± 148 | 15 ± 11 | 0·57 |
IL-8 | 4620 ± 1842 | 3349 ± 1936 | 0·75 |
IL-6 | 8 ± 2 | 6 ± 2 | 0·55 |
IL-4 | 0 | 373 ± 364 | 0·13 |
IL-5 | 1063 ± 1063 | 2167 ± 1665 | 0·51 |
IL-2 | 112 ± 52 | 59 ± 34 | 0·62 |
IL-1β | 347 ± 201 | 919 ± 644 | 0·73 |
CCL3 | 448 ± 272 | 736 ± 414 | 0·74 |
CXCL9 | 54 ± 14 | 223 ± 123 | 0·42 |
CXCL10 | 138 ± 39 | 84 ± 21 | 0·34 |
IFN = interferon; TNF = tumour necrosis factor; IL = interleukin; CCL = C-C chemokine ligand; CXCL = chemokine (C-X-C motif) ligand.