Fig 1.

Neutrophil and monocyte reactive oxygen intermediate (ROI) in infants with neonatal encephalopathy (NE) versus controls: whole blood from healthy adult controls (n = 15), neonatal controls (n = 8) and NE patients (n = 23) was incubated with lipopolysaccharide (LPS) ± activated protein C (APC) for 1 h and then stimulated with dihydrorhodamine 12 (DHR) and phorbol 12-myristate 13-acetate (PMA). Results were expressed as the Ln mean channel fluorescence ± standard error of the mean (s.e.m.). (a) Neutrophil reactive oxygen intermediate (ROI): *P < 0·05 versus controls; **P < 0·05 versus LPS response. (b) Monocyte ROI: *P < 0·05 versus adult and neonatal controls; **P < 0·05 versus NE baseline.