Table 1.

Clinical effects and colon length at end of last cycle in complement-deficient mice with chronic dextran sulphate sodium (DSS)-induced colitis

Group	Weight change	Stool	Colon length (cm)
WT	22·73% gain	Normal	6·8
WT+ DSS	11·8% gain	Soft	5·46
FB–/–	18% gain	Normal	6·5
FB–/– + DSS	13% gain	Soft	5·6
C3–/–	21% gain	Normal	6·6
C3–/– + DSS	6% gain*	Bloody diarrhoea	2·25#

^*P < 0·01 versus wild-type (WT) + DSS;

^#P < 0·01 versus WT + DSS and fB^–/– + DSS. Results expressed as mean, n = 8–12.