Table 1.
Summary of covariate data
| Pegaptanib dosage
|
Total N=58 |
|||
|---|---|---|---|---|
| 0.3 mg n=20 |
1.0 mg n=23 |
3.0 mg n=15 |
||
| Discrete, n (%) | ||||
| Race | ||||
| Asian | 1 (1.72) | 1 (1.72) | 0 (0.00) | 2 (3.45) |
| Black | 3 (5.17) | 3 (5.17) | 2 (3.45) | 8 (13.79) |
| Hispanic | 1 (1.72) | 1 (1.72) | 2 (3.45) | 4 (6.90) |
| White | 15 (25.86) | 18 (31.03) | 11 (18.97) | 44 (75.86) |
| Total | 20 (34.48) | 23 (39.66) | 15 (25.86) | 58 (100.00) |
| Sex | ||||
| Female | 11 (18.97) | 16 (27.59) | 5 (8.62) | 32 (55.17) |
| Male | 9 (15.52) | 7 (12.07) | 10 (17.24) | 26 (44.83) |
| Total | 20 (34.48) | 23 (39.66) | 15 (25.86) | 58 (100.00) |
| Continuous | ||||
| Age, years | ||||
| Mean | 60.75 | 62.83 | 61.27 | 61.71 |
| Median | 60.50 | 64.00 | 62.00 | 61.50 |
| SD | 11.80 | 12.74 | 10.05 | 11.61 |
| Minimum | 44.00 | 27.00 | 42.00 | 27.00 |
| Maximum | 89.00 | 81.00 | 76.00 | 89.00 |
| CRCL, mL/min | ||||
| Mean | 85.12 | 66.38 | 85.09 | 77.68 |
| Median | 77.10 | 64.31 | 73.27 | 70.48 |
| SD | 39.77 | 25.78 | 29.03 | 32.80 |
| Minimum | 36.07 | 29.94 | 46.18 | 29.94 |
| Maximum | 189.54 | 123.49 | 135.96 | 189.54 |
| Weight, kg | ||||
| Mean | 83.46 | 85.33 | 92.63 | 86.58 |
| Median | 84.45 | 83.50 | 90.30 | 85.15 |
| SD | 19.77 | 14.24 | 24.46 | 19.21 |
| Minimum | 47.20 | 59.50 | 51.10 | 47.20 |
| Maximum | 123.50 | 109.40 | 129.40 | 129.40 |
Notes: All covariates summary measures are from baseline/screening (prior to treatment) values.
Abbreviations: N, total number of patients; n, number of patients in subgroup; SD, standard deviation; CRCL, creatinine clearance based on the Crockroft-Gault formula; min, minute.