Table S2.

Number of patients, observations, BLQs, and exclusions

Sample type		Pegaptanib dose group			Total
		0.3 mg	1.0 mg	3.0 mg
Patients	n	20	23	15	58
	Row, %	34.5	39.7	25.9	100
Observations
>BLQ	No. of PK samples	102	173	131	406
	%	18.4	31.2	23.6	73.2
	Row, %	25.1	42.6	32.3	–
	Col, %	52.6	80.8	89.1	–
≤BLQ	No. of PK samples	92	40	12	144
	%	16.6	7.2	2.2	26.0
	Row, %	63.9	27.8	8.3	–
	Col, %	47.4	18.7	8.2	–
Excludeda	No. of PK samples	0	1	4	5
	%	0.00	0.18	0.72	0.90
	Row, %	0.00	20.0	80.0	–
	Col, %	0.00	0.47	2.72	–
Total	No. of PK samples	194	214	147	555
	%	35.0	39.6	26.5	100

Note:

^aExcluded from the analysis.

Abbreviations: BLQ, below the lower limit of quantification; No., number; PK, pharmacokinetic; Col, column.