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. 2015 Jan 8;172(5):1379–1394. doi: 10.1111/bph.13016

Figure 7.

Figure 7

Effects of 17β-oestradiol, ICI 182 780 and endoxifen on DiI-LDL uptake by lymphocytes. (A) Lymphocytes from four male donors were treated with DiI-LDL and vehicle, tamoxifen (TAM), raloxifene (RAL), toremifene (TOR), 17β-oestradiol (E2), 1 μM ICI 182 780 or the combinations of these drugs for 24 h as indicated. Data (mean ± SEM) are expressed as % of the condition without any drug added of the same cell preparation. (B) Lymphocytes from five male donors were treated with DiI-LDL and vehicle, TAM, E2, endoxifen (END), 1 μM ICI 182 780 or the combinations of these drugs for 24 h as indicated. Data (mean ± SEM) are expressed as % of the condition without any drug added of the same cell preparation. Statistical analyses were performed by two-way RM anova and post hoc by Student–Newman–Keuls test. **P < 0.01, ***P < 0.001 versus control; ###P < 0.001 versus RAL; §§§P < 0.001 versus TOR; ●P < 0.05, ●●●P < 0.001 versus 5 μM E2. For simplicity, the statistical differences between the conditions within the presence of ICI 182 780 were omitted.