Table 1.

Effect of SERMs on the incorporation of [³H]-oleic acid into cholesteryl esters by lymphocytes

	Subject 1	Subject 2	Subject 3	P versus control
Control	100.0	100.0	100.0	–
TAM	32.3	48.8	60.8	0.001
RAL	42.0	70.1	61.7	0.002
TOR	52.1	70.1	80.8	0.003

Lymphocytes from three male donors were treated with 60 μg·mL⁻¹ LDL plus vehicle (control) or 5 μM tamoxifen (TAM), raloxifene (RAL) or toremifene (TOR) for 24 h. [³H] oleic acid was added 2 h after adding the treatments. ³H-dpm·mg⁻¹ cell protein was calculated, and the results are expressed as % of the control of the same cell preparation. Statistical analysis was performed by one-way RM anova and post hoc by Student–Newman–Keuls test.