Table II.
Collection of the top ten deregulated lncRNAs detected using microarray analysis in ten CTEPH and control samples.
| Downregulated in CTEPH tissues | Upregulated in CTEPH tissues | ||||
|---|---|---|---|---|---|
|
|
|
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| lncRNA | P-value | Fold changea | lncRNA | P-value | Fold changea |
| NR_003679 | 5.70×10−6 | 0.45 | TCONS_l2_00010131-XLOC_l2_005462 | 3.00×10−5 | 5.89 |
| NR_033766 | 2.14×10−5 | 0.16 | TCONS_l2_00011539-XLOC_l2_005705 | 3.00×10−5 | 5.89 |
| TCONS_l2_00004769-XLOC_l2_002469 | 3.52×10−5 | 0.41 | NR_026544 | 1.16×10−4 | 2.61 |
| TCONS_00023959-XLOC_011280 | 4.21×10−5 | 0.49 | TCONS_00009277-XLOC_004803 | 1.18×10−4 | 1.82 |
| TCONS_00023957-XLOC_011280 | 4.96×10−5 | 0.52 | TCONS_l2_00016084-XLOC_l2_008434 | 1.24×10−4 | 2.02 |
| NR_026799 | 6.78×10−5 | 0.39 | NR_028406 | 2.36×10−4 | 2.17 |
| TCONS_l2_00020176-XLOC_l2_010319 | 9.89×10−5 | 0.32 | TCONS_00000337-XLOC_000468 | 4.50×10−4 | 2.42 |
| NR_026985 | 1.29×10−4 | 0.46 | NR_002433 | 5.00×10−4 | 2.46 |
| TCONS_00000192-XLOC_000173 | 1.42×10−4 | 0.28 | TCONS_00028854-XLOC_013966 | 5.18×10−4 | 1.89 |
| NR_026597 | 1.56×10−4 | 0.45 | NR_033652 | 5.66×10−4 | 1.91 |
a
Fold change vs. healthy control tissues.
lncRNA, long noncoding RNA; CTEPH, chronic thromboembolic pulmonary hypertension.