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. Author manuscript; available in PMC: 2015 Feb 23.
Published in final edited form as: Ann Surg Oncol. 2011 Sep 27;18(11):3164–3173. doi: 10.1245/s10434-011-1920-z

TABLE 5.

Multivariate Cox proportional hazard model for survival

Characteristic DMFS OS


HR 95% CI P-value HR 95% CI P-value
Mastectomy vs. BCT 1.32 1.1 to 1.59 0.003 1.22 1.02 to 1.47 0.032
Age: >50 vs. ≤ 50 0.74 0.61 to 0.89 0.001 0.93 0.77 to 1.11 0.40
Tumor size: T2–4 vs. T1 1.63 1.35 to 1.97 <0.0001 1.66 1.38 to 2.01 <0.0001
Lymph nodes: N1–3 vs. N0 1.44 1.19 to 1.75 0.0002 1.45 1.20 to 1.77 0.0002
Grade: III vs. I/II 1.25 0.95 to 1.66 0.11 1.36 1.03 to 1.80 0.031
LVI: positive vs. negative/unknown 1.62 1.35 to 1.94 <0.0001 1.56 1.30 to 1.87 <0.0001
Resection margin: close/positive vs. free 1.49 1.12 to 1.98 0.006 1.29 0.96 to 1.73 0.09
Adjuvant chemotherapy: anthracycline or taxane vs. anthracycline + taxane 0.90 0.74 to 1.09 0.29 0.90 0.74 to 1.10 0.30
Adjuvant chemotherapy: other vs. anthracycline + taxane 1.68 1.29 to 2.19 0.0001 1.40 1.06 to 1.84 0.017