TABLE 5.
Multivariate Cox proportional hazard model for survival
| Characteristic | DMFS | OS | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Mastectomy vs. BCT | 1.32 | 1.1 to 1.59 | 0.003 | 1.22 | 1.02 to 1.47 | 0.032 |
| Age: >50 vs. ≤ 50 | 0.74 | 0.61 to 0.89 | 0.001 | 0.93 | 0.77 to 1.11 | 0.40 |
| Tumor size: T2–4 vs. T1 | 1.63 | 1.35 to 1.97 | <0.0001 | 1.66 | 1.38 to 2.01 | <0.0001 |
| Lymph nodes: N1–3 vs. N0 | 1.44 | 1.19 to 1.75 | 0.0002 | 1.45 | 1.20 to 1.77 | 0.0002 |
| Grade: III vs. I/II | 1.25 | 0.95 to 1.66 | 0.11 | 1.36 | 1.03 to 1.80 | 0.031 |
| LVI: positive vs. negative/unknown | 1.62 | 1.35 to 1.94 | <0.0001 | 1.56 | 1.30 to 1.87 | <0.0001 |
| Resection margin: close/positive vs. free | 1.49 | 1.12 to 1.98 | 0.006 | 1.29 | 0.96 to 1.73 | 0.09 |
| Adjuvant chemotherapy: anthracycline or taxane vs. anthracycline + taxane | 0.90 | 0.74 to 1.09 | 0.29 | 0.90 | 0.74 to 1.10 | 0.30 |
| Adjuvant chemotherapy: other vs. anthracycline + taxane | 1.68 | 1.29 to 2.19 | 0.0001 | 1.40 | 1.06 to 1.84 | 0.017 |