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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Med Res Rev. 2014 May 14;35(1):1–62. doi: 10.1002/med.21319

Table XXI.

Cytotoxicity Data for Indole-Substituted Analogs 568–574

graphic file with name nihms-662637-t0048.jpg
IC50 (μM)
Compound HeLa K562 K562/AO2 KB KBV
ETO 2.11 ± 1.17 0.9 ± 0.08 7.05 ± 5.08 3.36 ± 1.05 55.47 ± 4.36
568 1.05 0.99 ± 0.60 4.04 ± 0.97 3.99 ± 1.28 6.28 ± 2.05
569 5.237 0.29 ± 0.19 0.12 ± 00.6 2.49 ± 0.94 3.49 ± 1.05
570 3.805 0.23 ± 0.16 0.70 ± 0.02 0.88 ± 0.23 3.62 ± 2.17
571 0.15 0.40 ± 0.14 0.29 ± 0.26 1.00 ± 0.78 3.16 ± 1.46
572 0.73 1.22 ± 0.35 0.62 ± 0.28 4.99 ± 1.36 5.46 ± 3.65
573 10.67 0.31 ± 0.18 0.22 ± 0.20 1.03 ± 0.38 2.59 ± 0.28
574 11.11 0.46 ± 0.37 0.10 ± 0.01 1.62 ± 1.25 2.30 ± 2.17
a

Cytotoxicity against HeLa, KB, and KBV cell lines and against K562 and K562/AO2 cell lines measured by standard MTT and SRB assay methods, respectively.

b

Each value represents mean ± SD of three independent experiments.