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Cytotoxicity Data for Ester Analogs 258–267
| ||||||
|---|---|---|---|---|---|---|
| IC50 (μM) |
Kidney fibroblast VERO cells |
|||||
| Compound | SK-MEL | KB | BT-549 | SK-OV-3 | HL-60 | |
| PPT | 0.22 | 0.24 | 0.36 | 0.19 | 0.01 | 0.55 |
| 258 | 0.21 | 0.31 | 0.22 | 0.26 | 0.07 | NA |
| 259 | 0.41 | 1.19 | 0.29 | 0.44 | 0.19 | NA |
| 260 | 0.89 | NA | 1.19 | 0.76 | 0.24 | NA |
| 261 | 0.90 | 2.39 | 0.85 | 0.81 | 0.18 | NA |
| 262 | 4.0 | 4.30 | 2.59 | 3.75 | 0.47 | NA |
| 263 | 0.34 | 0.40 | 0.27 | 0.27 | 0.07 | NA |
| 264 | 1.17 | 1.35 | 1.08 | 1.08 | 0.24 | NA |
| 265 | 1.42 | 1.42 | 0.89 | 0.79 | 0.85 | NA |
| 266 | NA | NA | NA | NA | NA | NA |
| 267 | NA | NA | NA | NA | NA | NA |
