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Cytotoxicity Data for Ester Analogs 268–277
| ||||||
|---|---|---|---|---|---|---|
| IC50 (μM) |
||||||
| Compound | SK-MEL | KB | BT-549 | SK-OV-3 | HL-60 | VERO |
| PPT | 0.22 | 0.24 | 0.36 | 0.19 | 0.01 | 0.55 |
| 268 | 0.45 | 1.26 | 4.76 | 0.17 | 0.66 | NA |
| 269 | 8.12 | NA | 7.50 | 10.64 | 0.22 | NA |
| 270 | NA | NA | NA | NA | 0.73 | NA |
| 271 | NA | NA | NA | NA | NA | NA |
| 272 | NA | NA | NA | NA | NA | NA |
| 273 | 0.72 | 2.4 | 1.2 | 0.84 | 0.58 | NA |
| 274 | 1.87 | 2.2 | 2.53 | 0.77 | 0.55 | NA |
| 275 | NA | 0.93 | 1.33 | NA | 0.08 | NA |
| 276 | 0.30 | 0.45 | 0.30 | 0.30 | 0.10 | NA |
| 277 | 2.9 | 0.35 | 0.81 | NA | 0.07 | NA |
