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. Author manuscript; available in PMC: 2016 Feb 12.
Published in final edited form as: J Med Chem. 2015 Jan 23;58(3):1307–1319. doi: 10.1021/jm5015742

Fig 3.

Fig 3

In vivo evaluation of the antichagasic efficacy of compounds 2, 5, 18 and 19 in the acute murine model. Benznidazole (Bnz) data from 2 experiments in parallel were included. All compounds except 5 were administered (i.p.) at 15 mg/kg/day. Compound 5 was administered (i.p.) at 13 mg/kg/day. The P values refer to comparisons between treated groups and control group. When P values are not given, there was no statistical difference. Groups of 5 mice/group were used. Occasionally, 10 mice were used in the control group.