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. Author manuscript; available in PMC: 2015 Feb 23.
Published in final edited form as: Nucl Med Commun. 2011 Nov;32(11):1046–1051. doi: 10.1097/MNM.0b013e32834a369b

Fig. 2.

Fig. 2

Number of foci detected using laser confocal microscopy and fluorescent Fluor 647 anti-H2A.X-phosphorylated (Ser139) antibody. Double-stranded breaks (red) are clearly augmented in cells incubated with 500 nmol/l of ABT-888 and 500 nmol/l of AZD-2281 compared with PBS and 1% dimethyl sulfoxide controls. Image analysis was performed using ImageJ and the ‘analyze particle’ function.