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. Author manuscript; available in PMC: 2015 Feb 23.
Published in final edited form as: Nucl Med Commun. 2011 Nov;32(11):1046–1051. doi: 10.1097/MNM.0b013e32834a369b

Fig. 3.

Fig. 3

Colorimetric poly(ADP-ribose) polymerase (PARP) activity assay showing the relative activity of the PARP-1 enzyme in Raji lymphocyte tumor cells. Results show a highly significant difference in PARP activity in the controls [PBS and dimethyl sulfoxide (DMSO)] compared with 24 h incubation with 500 nmol/l of ABT-888 and 500 nmol/l of AZD-2281. A significant increase in PARP enzyme activity is shown in DMSO-incubated cells compared with PBS control. *P<0.05.