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. Author manuscript; available in PMC: 2015 Feb 23.
Published in final edited form as: J Biol Regul Homeost Agents. 2014 Oct-Dec;28(4):587–603.

Figure 6. Inhibitory profile of PK activation BY CTI in cell-free system.

Figure 6

A, PK activation by FXII in the absence of CTI is shown. Using 0.156 µM and 10 µM, CTI inhibited activation of PK by factor XII (FXII) in dose-dependent manner (p=0.0161 and p=0.000176 for 0.156 µM and 10 µM, respectively, n=3). B, 40 µg of plasma membrane fraction (Pmb) of VSMC activated PK was not inhibited by 0.156 µM and 10 µM of CTI (p=0.996 and p=0.906 for 0.156 µM and 10 µM, respectively, n=3). C, Cytosolic fraction also activated PK, which did not show a significant inhibition by 0.156 µM and 10 µM of CTI (p=0.165 and p=0.765 for 0.156 µM and 10 µM, respectively, n=3).