(A).Adsorption of HIV-1 particles by scFv-VRC01 surface displayed bacteria. The engineered bacteria with the concentration of 108/ml mixed with the viral stock can reduce the viral titer by surface binding. HIV-1 strains: YU2 (R5 virus, subtype B), 1084i (R5 virus, subtype C), HXBc2 (X4 virus, subtype B), AMLV, unrelated virus. RT, reverse transcriptase. (B). Inhibition of viral infection by scFv-VRC01 surface displayed bacteria in vitro. The target cells (Cf2Th) stably expressed receptor CD4 and co-receptor CCR5 were used for infection, and the luciferase was a reporter gene. HIV-1 strains: YU2 (R5 virus, subtype B), 1084i (R5 virus, subtype C), HXBc2 (X4 virus, subtype B) as negative control, AMLV, unrelated virus.