TABLE 1.
Phenotypic and molecular typing data of six mecC methicillin-resistant Staphylococcus aureus isolates
| Isolate 4402/2009 |
Isolate 5127/2010 |
Isolate 5590/2012 |
Isolate 5625/2012 |
Isolate 5676/2012 |
Isolate 5752/2013 |
|
|---|---|---|---|---|---|---|
| Disk diffusion test | Diameter (mm) (category) | Diameter (mm) (category) | Diameter (mm) (category) | Diameter (mm) (category) | Diameter (mm) (category) | Diameter (mm) (category) |
| Cefoxitin | 18 (mean, R) | 16 (mean, R) | 21 (mean, R) | 18 (mean, R) | 17 (mean, R) | 20 (mean, R) |
| Gentamicin | 20 (S) | 22 (S) | 20 (S) | 22 (S) | 24 (S) | 22 (S) |
| Erythromycin | 26 (S) | 26 (S) | 24 (S) | 28 (S) | 30 (S) | 30 (S) |
| Clindamycin | 25 (S) | 26 (S) | 22 (S) | 26 (S) | 30 (S) | 30 (S) |
| Tetracycline | 25 (S) | 26 (S) | 22 (S) | 27 (S) | 25 (S) | 30 (S) |
| Fusidic acid | 30 (S) | 31 (S) | 26 (S) | 30 (S) | 30 (S) | 30 (S) |
| Trimethoprim/sulfa | 32 (S) | 31 (S) | 26 (S) | 34 (S) | 30 (S) | 30 (S) |
| Rifampicin | 31 (S) | 30 (S) | 27 (S) | 32 (S) | 30 (S) | 30 (S) |
| Gradient MIC test | MIC (mg/L) | MIC (mg/L) | MIC (mg/L) | MIC (mg/L) | MIC (mg/L) | MIC (mg/L) |
| Ceftaroline | 1 (S) | 1 (S) | 1 (S) | 1 (S) | 0.5 (S) | 0.5 (S) |
| Vancomycin | 1 (S) | 1 (S) | 2 (S) | 1 (S) | 1 (S) | 2 (S) |
| Teicoplanin | 1 (S) | 1 (S) | 2 (S) | 1 (S) | 1 (S) | 0.25 (S) |
| Tigecycline | 0.25 (S) | 0.25 (S) | 0.25 (S) | 0.25 (S) | 0.125 (S) | 0.25 (S) |
| Linezolid | 0.5 (S) | 0.5 (S) | 1 (S) | 0.5 (S) | 0.5 (S) | 2 (S) |
| Daptomycin | 0.25 (S) | 0.125 (S) | 0.125 (S) | 0.125 (S) | 0.25 (S) | 0.25 (S) |
| Fosfomycin | 1 (S) | 1 (S) | 0.5 (S) | 1 (S) | 0.5 (S) | 2 (S) |
| Oxacillin | 4 | 4 | 2 | 8 | 4 | 2 |
| Cefoxitin | 16 | 32 | 16 | 16 | 32 | 16 |
| Typing | ||||||
| Multilocus sequence | 599 | 130 | SLV of 130 | 130 | 599 | 130 |
| Type | ||||||
| Clonal complex | 599 | 130 | 130 | 130 | 599 | 130 |
| spa Type | t5930 | t3256 | t1535 | t1535 | t5930 | t843 |
| Virulence factor gene | ||||||
| tst | + | − | − | − | + | − |
| lukED | + | + | + | + | + | + |
| eta | + | + | + | + | + | + |
| etd2 | − | + | + | + | − | + |
| edin-B | − | + | + | + | − | + |
| sel | + | − | − | − | + | − |
SLV, single locus variant; MIC, minimum inhibitory concentration.