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. Author manuscript; available in PMC: 2015 Feb 23.
Published in final edited form as: Ann Surg Oncol. 2013 Aug 23;20(13):4103–4112. doi: 10.1245/s10434-013-3194-0

TABLE 4.

Rates of locoregional recurrence (LRR) and contralateral breast cancer development by margin status in patients with ductal carcinoma-in situ treated with mastectomy (n = 810)

LRR Margins positive or ≤1 mm (%) Margins 1. 1–2.9 mm (%) Margins ≥ 3 mm (%) p value, overalla p value, positive or ≤1 versus ≥1.1a p value, positive or ≤1 versus 1.1–2.9a
5-year LRR rate, entire series 4.5 3.5 0.7 <0.001 <0.001 0.574
10-year LRR rate, entire series 4.5 3.5 0.7 <0.001 <0.001 0.574
5-year LRR rate, patients who did not receive radiotherapy (n = 803) 5.0 3.6 0.7 <0.001 <0.001 0.531
10-year LRR rate, patients who did not receive radiotherapy (n = 803) 5.0 3.6 0.7 <0.001 <0.001 0.531
10-year rate of development of contralateral breast cancer (n = 546)b 6.8 0 6.7 0.529 0.934 0.248
a

Calculated by the Kaplan–Meier method. Differences were compared by the log-rank test

b

Excludes patients who had contralateral prophylactic mastectomy, bilateral breast cancer at diagnosis, or history of contralateral breast cancer