Table 1.

Microarray analysis of enriched white matter from the corpus callosum indicates multiple pathways involved in the response to hypoperfusion

Database	Biological process	Observed	Expected	p value
GO	Regulation of cell proliferation	15	3.66	0.001
GO	Angiogenesis	9	1.23	0.001
KEGG	Jak–STAT signaling pathway	7	1.06	0.0027
KEGG	Complement and coagulation cascades	5	0.54	0.0029
GO	Organ development	28	12.89	0.0037
GO	Blood vessel morphogenesis	9	1.7	0.0037
GO	Blood vessel development	10	2.07	0.0037
GO	Vasculature development	10	2.11	0.0037
GO	Anatomical structure formation/morphogenesis	12	2.88	0.0037
KEGG	Cytokine–cytokine receptor interaction	8	1.79	0.0039
GO	Cell adhesion	14	4.34	0.0048
GO	Cell proliferation	15	4.99	0.0048
GO	Anatomical structure development	32	16.39	0.0048
KEGG	Acute myeloid leukemia	4	0.42	0.0058

Genes (n = 129) altered (p < 0.001) were uploaded to WebGestalt enrichment analysis based on Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. Biological processes [adjusted p < 0.01 (Benjamini and Hochberg, 1995)] from both Gene Ontology and Kyoto Encyclopedia of Genes and Genomes databases, along with the observed and expected number of molecules represented for each category, are listed.