Table 1. The list of differentially methylated genes in mutant IDH1 expressing NHAs was downloaded from the supplementary information provided in the Turcan et al. paper [9] and mined for genes associated with the metabolites identified to be altered in mutant IDH1 cells in our study.
| Probeset ID | Symbol | Normalized fold change (IDHmut/ IDHwt) | Delta-beta (P40 mut vs P40 wt) | Relation to UCSC CpG island | Q value |
|---|---|---|---|---|---|
| cg16490209 | BCAT1 | 5.8 | 0.1885695 | N_Shelf | 0.0463618 |
| cg11956052 | BCAT2 | 23.1 | 0.2472525 | N_Shore | 0.0426788 |
| cg01505421 | CHKB | 1.5 | 0.01728 | N_Shore | 0.0437283 |
| cg18555289 | GPT | 8.4 | 0.132311 | N_Shore | 0.0382745 |
| cg00270789 | GPT2 | 11.8 | 0.251366 | S_Shore | 0.0382745 |
| cg00242020 | GOT1L1 | 14.8 | 0.1955245 | 0.0417852 | |
| cg03177631 | LDHA | 1.3 | 0.00801755 | Island | 0.0391234 |