Table 2. Characteristics of patients within the spatio-temporal clusters compared to patients outside the spatio-temporal clusters.
| Not in spatio-temporal cluster (ref) | Southwestern spatio-temporal cluster | Northeastern spatio-temporal cluster | |||
|---|---|---|---|---|---|
| n = 746 | n = 96 | n = 39 | |||
| n (%) | n (%) | p-value* | n (%) | p-value* | |
| Sex | |||||
| Men | 570 (76.4) | 79 (82.3) | 0.197 | 36 (92.3) | 0.021 |
| Women | 176 (23.6) | 17 (17.7) | 3 (7.7) | ||
| Age | |||||
| Median (IQR) | 42 (30–53) | 43 (29.5–53.5) | 0.937 | 46 (42–54) | 0.057 |
| Ethnicity | |||||
| Dutch | 594 (79.6) | 75 (78.1) | 0.403 | 37 (94.9) | 0.053 |
| Non-Dutch | 126 (16.9) | 15 (15.6) | 1 (2.6) | ||
| Unknown | 26 (0.1) | 6 (6.3) | 1 (2.6) | ||
| Transmission route | |||||
| Heterosexual men | 155 (20.8) | 24 (25.0) | 0.096 | 2 (5.1) | 0.003 |
| MSM | 198 (26.5) | 28 (29.2) | 13 (33.3) | ||
| Women—sex. contact | 127 (17.0) | 16 (16.7) | 3 (7.7) | ||
| Other | 57 (7.6) | 12 (12.5) | 2 (5.1) | ||
| Unknown—men | 177 (23.7) | 16 (16.7) | 19 (48.7) | ||
| Unknown—women | 32 (4.3) | 0 (0.0) | 0 (0.0) | ||
| Number sequenced | |||||
| C-gene | 343 (46.0) | 28 (29.2) | 0.002 | 27 (69.2) | 0.005 |
| Median cluster size (IQR) | |||||
| C-gene | 7 (1–54) | 3.5 (1–51) | 0.901 | 51 (51–70) | <0.0001 |
| Genetic cluster ≥ 3 | |||||
| C-gene | 193 (56.3) | 16 (57.1) | 0.929 | 23 (85.2) | 0.003 |
*Compared to patients not in a spatio-temporal cluster.