Table 2. Amphibian ranaviruses included in this study.
| Virus | Acronym / No. | Host species | Country of origin | Year of detection | Short case history/clinical signs | Reference(s) | GenBank IDs |
|---|---|---|---|---|---|---|---|
| Zuerich Pelophylax collection ranavirus 1* | ZPRV1 | Edible frog Pelophylax kl. esculentus | Switzerland (imported from Germany) | 2008 | Reddening of the skin (legs, abdomen), haemorrhages in the gastrointestinal tract, mass mortality event. | [34] | KC440841; KC440846; KC440843; KC440845; vIF-2α: KM516749* |
| Zuerich Pelophylax collection ranavirus 2* | ZPRV2 | Edible frog Pelophylax kl. esculentus | Switzerland (imported from unknown European country) | 2010 | Reddening of the skin (legs, abdomen), haemorrhages in the gastrointestinal tract, mass mortality event. | [34] | KC440842; KC440847; KC440844; KC440845; vIF-2α: KM516750* |
| Neurergus crocatus ranavirus* | NCRV | Lake Urmia newt Neurergus crocatus | Germany (imported from Iraq) | 2011 | Ulcerative dermatitis, systemic haemorrhages, high mortality. | [33] | MCP: KM516717*; DNApol: KM516726*; RNR-α: KM516735*; RNR-β: KM516744*; vIF-2α: KM516755* |
| Portuguese newt and toad ranavirus* | PNTRV | Common midwife toad Alytes obstetricians; Bosca’s newt Lissotriton boscai | Portugal (Serra da Estrela) | 2013 | unpublished | Rosa et al., unpublished | MCP: KM516718*; DNApol: KM516727*; RNR-α: KM516736*; RNBR-β: KM516745*; vIF-2α: KM516756* |
| Frog virus 3 | FV3 | Leopard frog Lithobates pipiens | America | 1965 | Renal adenocarcinoma. Type species of the genus Ranavirus. | [60] | AY548484 |
| Bohle iridovirus | BIV | Burrowing frog Lymnodynastes ornatus | Australia | 1992 | Moribund tadpoles | [61] | AY187046; FJ374280; GU391286; GU391264; EF408913 |
| Rana grylio iridovirus | RGV | Pig frog Rana grylio | China | 1995 | Mass mortality in cultured frogs | [62] | JQ654586 |
| Ambystoma tigrinum virus | ATV | Tiger salamander Ambystoma tigrinum stebbinsi | USA | 1996 | Haemorrhages of the skin and internal organs, lethargy, high mortality. | [63] | AY150217 |
| Tiger frog virus | TFV | Tiger frog Rana tigrina rugulosa | China | 2000 | Abdominal distension, ataxia, petechial haemorrhages in different organs, high mortality in cultured animals. | [64] | AF389451 |
| Rana esculenta virus Italy 282/I02 | REV 282/I02 | Edible frog Pelophylax esculentus | Italy | unknown | Moribund tadpoles of wild frogs, diseased short after removal from their habitat. | [13] | FJ358611; FJ374275; GU391293; GU391271 |
| Common midwife toad virus | CMTV | Common midwife toad Alytes obstetricians; Alpine newt Ichthyosaura alpestris cyreni | Spain | 2007 | Mass-mortality event in wild animals | [65, 66] | JQ231222 |
| Water frog Pelophylax spp.; Common newt Lissotriton vulgaris | Netherlands | 2010 | Mass-mortality event in wild animals. | [67] | |||
| Andrias davidianus ranavirus | ADRV | Chinese giant salamander Andrias davidianus | China | 2011 | Epidemic disease with high mortality, systemic haemorrhage and swelling syndrome | [68] | KC865735 |
The different viruses are presented with reference to host species, country and year of first detection, short case history and references.
Virus / GenBank accession numbers highlighted bold*: new sequences were obtained during this study; sequences from nonmarked viruses were obtained from GenBank.