Table 1. Characteristics of the Leipzig Adipose Tissue Childhood Cohort.
| CHILDREN | ADULTS | |||||
|---|---|---|---|---|---|---|
| Lean | Obese | p | Lean | Obese | p | |
| N | 87 | 44 | 9 | 14 | ||
| female/male [n] | 34/53 | 19/25 | 0.651 | 7/2 | 6/8 | 0.099 |
| Age [years] | 6.9 ±0.6 | 10.8 ±0.7 | <0.001 | 55.4 ±6.7 | 61.2 ±3.8 | 0.369 |
| (0.1–18.2) | (0.4–18.3) | (27.5–78.1) | (37.8–89.2) | |||
| BMI-SDS | -0.4 ±0.1 | 2.2 ±0.1 | <0.001 | -0.5 ±0.2 | 0.4 ±0.2 | <0.016 |
| (-2.5–1.2) | (1.3–3.6) | (-1.6–0.2) | (-0.5–1.9) | |||
| BMI [kg/m²] | 16.6 ±0.2 | 26.6 ±0.7 | <0.001 | 23.9 ±0.4 | 28.4 ±0.8 | <0.001 |
| (12.5–23) | (17.8–34.5) | (21.8–25) | (25.5–35.1) | |||
| PH | <2 | >2 | 0.001 | |||
| (1–5) | (1–6) | |||||
| Adipocyte area [μm²] | 3605.0 ±223.6 | 5206.9 ±316.0 | <0.001 | 6901.6 ±271.2 | 5873.3 ±319.3 | 0.072 |
| (407–10200) | (680–8557) | (6162–7571) | (3626–7558) | |||
| Depots | ||||||
| Subcutaneous | 80 | 43 | 9 | 14 | ||
| Perirenal | 5 | 1 | ||||
| Visceral | 2 | |||||
Data are given as mean ± SEM (range). For gender, statistical significance was analysed by chi square test. Statistical significance for differences between lean and obese individuals was determined by Students t-test. Significant p-values are indicated in bold. BMI, body-mass index; SDS, standard deviation score; PH, pubertal stage.