Table 4. Association between haplotypes of the three tagSNPs in SIRT1 gene with the risk of MI.
| Haplotype a | Controls (n = 654) No. (%) | Cases (n = 287) No. (%) | OR (95% CI) | P | P c |
|---|---|---|---|---|---|
| C A C | 562.99 (43.0) | 240.87 (42.0) | 0.96 (0.79–1.17) | 0.678 | NS |
| C A T | 200.01 (15.3) | 72.13 (12.6) | 0.80 (0.60–1.07) | 0.124 | NS |
| C G T | 364.99 (27.9) | 154.87 (27.0) | 0.96 (0.77–1.19) | 0.691 | NS |
| G A T | 179.00 (13.7) | 105.00 (18.3) | 1.41 (1.09–1.84) | 0.010 | 0.040 b |
P c, Bonferroni corrected P; NS, not significant.
a The allelic sequence in the haplotypes is in the following order: rs7069102, rs3818292, rs4746720.
b P c values under 0.05 were indicated in bold font.