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. 2015 Feb 23;10(2):e0117899. doi: 10.1371/journal.pone.0117899

Fig 1. Assessment of kidney weight, blood pressure, heart rate, locomotor activity, urinary output and urinary albumin excretion.

Fig 1

A) Kidney weights after 11 weeks of 2K1C. *p < 0.05. B) Weekly blood pressure measurements for 11 weeks after insertion of the renal artery clip. The difference in blood pressure between baseline and after clip placement is shown. *p < 0.001 vs. Control, **p < 0.0001 vs. Control. C) Circadian changes of blood pressure at baseline, 2 weeks and 11 weeks after clip placement. *p < 0.05 vs. light. D) Weekly heart rate measurements for 11 weeks of 2K1C. *p < 0.001 vs. baseline (0 weeks). E) Circadian changes of heart rate at baseline, 2 weeks and 11 weeks after clip placement. *p < 0.05 vs. light. F) Locomotor activity in mice over 11 weeks of 2K1C. G) Circadian changes of activity at baseline, 2 weeks and 11 weeks after clip placement. *p < 0.05, **p < 0.01, ***p < 0.001 vs. light. H) Urinary output at baseline and 1, 2, 3, 4, 6, 8, and 10 weeks after clip placement. I) Daily urinary albumin excretion at baseline and 1, 2, 3, 4, 6, 8, and 10 weeks after insertion of the renal artery clip *p < 0.0001 vs. Control.