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. 2015 Feb 23;10(2):e0118458. doi: 10.1371/journal.pone.0118458

Table 2. Differentially expressed genes in mastitis mammary tissues with respect to normal mammary tissues.

Gene symbol Representative public ID Normal Mastitis Fold-change [log2(m/n)]
Up-regulated genes in mastitis mammary tissues
TICAM2 NM_001046456 8.05 9.35 1.30
PIK3CA NM_174574 4.63 5.96 1.33
STAT1 NM_001077900 0.65 2.06 1.41
IL10 NM_174088 10.06 11.55 1.49
IKBKG NM_174354 -6.64 -4.98 1.66
MAPK11 NM_001080335 -6.64 -4.98 1.66
IFNAR2 NM_174553 2.48 6.85 1.77
TLR6 NM_001001159 2.48 3.32 1.78
CASP8 NM_001045970 -1.41 0.40 1.81
TAB2 NM_001192372 -1.41 0.40 1.81
MAPK8 NM_001192974 1.65 4.29 2.75
MAP2K2 NM_001038071 -1.41 2.06 3.47
MAPK10 NM_001083728 -1.41 2.48 3.90
MyD88 NM_001014382 -4.98 1.25 6.23
TLR9 NM_183081 -6.64 0.40 7.04
IRAK1 NM_001040555 -4.98 2.58 7.56
TLR4 NM_174198 -6.64 2.19 8.83
TLR7 NM_001033761 -6.64 2.58 9.22
IL6ST XM_600430 -1.41 0.40 1.81
Down-regulated genes in mastitis mammary tissues
CD14 molecule NM_174008 2.48 -4.98 -7.47
CXCL11 CK959898 1.87 -4.98 -6.86
MAPK14 NM_001102174 1.87 -4.98 -6.86
TLR3 NM_001008664 0.65 -4.98 -5.63
MAP2K3 NM_001083693 9.31 3.84 -5.47
NFKB1 NM_001076409 11.56 7.84 -3.72
IFNAC NM_174085 -1.41 -4.98 -3.57
IFNW1 NM_174351 -1.41 -4.98 -3.57
MAP2K6 NM_001034045 -1.41 -4.98 -3.57
TLR8 NM_001033937 -1.41 -4.98 -3.57
CXCL10 NM_001046551 6.49 2.98 -3.51
IRF5 NM_001035465 3.79 0.40 -3.40
TNF NM_173966 7.72 5.00 -2.72
IL12A CB168830 5.96 3.54 -2.42
AKT1 NM_173986 3.32 1.25 -2.07
RELA NM_001080242 5.21 3.32 -1.89
IRF7 NM_001105040 11.28 9.46 -1.82
IKBKE NM_001046345 2.19 0.40 -1.79
NFKBIA NM_001045868 5.40 3.66 -1.74
TLR1 NM_001046504 4.78 2.58 -1.65
JUN NM_001077827 5.40 4.25 -1.54
TBK1 NM_001192755 5.79 3.32 -1.45
MAPK13 NM_001014947 5.96 4.82 -1.38
IL1B NM_174093 7.43 6.14 -1.29
MAP3K7 NM_001081595 5.79 4.51 -1.29
PIK3CD NM_001205548 12.65 11.45 -1.19
FOS NM_182786 1.54 0.40 -1.15
IRAK4 NM_001075998 3.19 2.06 -1.13
IRF3 NM_001029845 3.62 2.58 -1.04