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. 2015 Feb 16;9:887–900. doi: 10.2147/DDDT.S78015

Figure 2.

Figure 2

Survival, loss of body weight, and motor function of R6/2 HD mice were improved under oral B401 treatment.

Notes: (A) Survival duration of R6/2 HD mice under oral B401 treatment was increased than those with sham treatment. (B) Body weight of R6/2 HD mice under oral B401 treatment (HD mice oral B401, n=22) was significantly greater than those with sham treatment (HD mice sham, n=20) from 8 weeks of age and thereafter. (C) Latencies to fall of R6/2 HD mice under oral B401 treatment (HD oral B401, n=16) were significantly increased than those with sham treatment (HD sham, n=15) from 8 weeks of age and thereafter as observed by rotarod testing. Values are mean ± SEM (**P<0.01, *P<0.05, one-way ANOVA followed by a Student–Newman–Keuls multiple comparisons posttest).

Abbreviations: HD, Huntington’s disease; SEM, standard error of the mean; ANOVA, analysis of variance.