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. 2015 Jan 16;4(3):210–221. doi: 10.1016/j.molmet.2015.01.004

Figure 3.

Figure 3

Changes in desaturation index associated FFA, TG, and PL fractions in liver and plasma in response to CNS NPY and Y1 receptor signaling. Plasma and/or liver samples from lean 4-h fasted rats (n = 5–6/group) were collected 60 min post icv injection of NPY (1 nmol; black bars) or the Y1 receptor agonist [F7, P34]-NPY (1 nmol; gray bars) or Veh (white bars). Desaturation index [(16:1 + 18:1)/(16:0 + 18:0)] of TG, FFA, and PL from liver (A) as well as plasma (B) in lean 4-h fasted NPY- (black bars) or Veh-treated (white bars) rats. Desaturation index of plasma TG, FFA, and PL from plasma (C) in lean 4-h fasted Y1 receptor agonist- (gray bars) or Veh-treated (white bars) rats. Data are presented as mean ± SEM and were analyzed by Student's t-test (unpaired, two-tailed); *indicates a significant difference (p < 0.05) between icv treatment vs. Veh.