Table 1.

Effects of NPY or the Y1 receptor agonist on glucoregulatory hormones and blood glucose at 60 min post-icv injection.

	NPY		Y1 agonist
Veh	NPY	Veh	Y1
Insulin (ng/ml)	0.80 ± 0.2	1.18 ± 0.2	2.99 ± 0.5	5.45 ± 0.4*
Glucagon (pg/ml)	101 ± 13	120 ± 13	100 ± 10	117 ± 10
Blood glucose (mg/dl)	127 ± 6.0	130 ± 9.2	153 ± 2.6	152 ± 4.0

Data are presented as mean ± SEM (n = 6–7/group) and were analyzed by Student's t-test (unpaired, two-tailed); *p < 0.01 for icv treatment vs. Veh comparison.